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Characterization of proteins (1988)

Public ISBD Titre : Characterization of proteins Type de document : texte imprimé Auteurs : Felix Franks, Éditeur scientifique Editeur : Chifton [new jersey] : Humana press Année de publication : 1988 Collection : Biological methods Importance : 1 vol. (xix-561 p) Présentation : ill Format : 23 cm ISBN/ISSN/EAN : 978-0-89603-109-8 Langues : Anglais (eng) Tags : Proteins Index. décimale : 574.1 Résumé : Proteins are the servants of life. They occur in all component parts of living organisms and are staggering in their functional var- ty, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different proteins, fulfilling a wide range of life-supporting roles. Their production is controlled by the cell's genetic machinery, and a malfunction of even one protein in the cell will give rise to pathological symptoms. Additions to the total number of known proteins are constantly being made on an increasing scale through the discovery of mutant strains or their production by genetic manipulation; this latter technology has become known as protein engineering. The in vivo functioning of proteins depends critically on the chemical structure of individual peptide chains, but also on the detailed folding of the chains themselves and on their assembly into larger supramolecular structures. The molecules and their fu- tional assemblies possess a limited in vitro stability. Special methods are required for their intact isolation from the source material and for their analysis, both qualitatively and quantitatively. Proteins are also increasingly used as "industrial components," e.g., in biosensors and immobilized enzymes, because of their specificity, selectivity, and sensitivity. This requires novel and refined proce- ing methods by which the protein isolate can be converted into a form in which it can be utilized. Characterization of proteins [texte imprimé] / Felix Franks, Éditeur scientifique . - Chifton [new jersey] : Humana press, 1988 . - 1 vol. (xix-561 p) : ill ; 23 cm. - (Biological methods) . ISBN : 978-0-89603-109-8 Langues : Anglais (eng) Tags : Proteins Index. décimale : 574.1 Résumé : Proteins are the servants of life. They occur in all component parts of living organisms and are staggering in their functional var- ty, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different proteins, fulfilling a wide range of life-supporting roles. Their production is controlled by the cell's genetic machinery, and a malfunction of even one protein in the cell will give rise to pathological symptoms. Additions to the total number of known proteins are constantly being made on an increasing scale through the discovery of mutant strains or their production by genetic manipulation; this latter technology has become known as protein engineering. The in vivo functioning of proteins depends critically on the chemical structure of individual peptide chains, but also on the detailed folding of the chains themselves and on their assembly into larger supramolecular structures. The molecules and their fu- tional assemblies possess a limited in vitro stability. Special methods are required for their intact isolation from the source material and for their analysis, both qualitatively and quantitatively. Proteins are also increasingly used as "industrial components," e.g., in biosensors and immobilized enzymes, because of their specificity, selectivity, and sensitivity. This requires novel and refined proce- ing methods by which the protein isolate can be converted into a form in which it can be utilized.

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
01746	biotechno-53	livres	Bibliothèque de la faculté S.N.V * HARCHE MERIEM*	livres	Consultation sur place Exclu du prêt

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